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Asked by galilsoilfarm ·September 23, 2018 ·24.5k readers

Papaya Leaf FPJ as a BioPesticide

Papaya leaves contain papain, a proteolytic enzyme which is a naturally occurring bio-pesticide. As such I was wondering if could apply Papaya Leaf FPJ as a pesticide?

The answer

From the KNF library

From the KNF library Drafted by Claude from Office Hours and the books · Sep 2026 · 5 sources

Drake recommends testing before you count on it. An Office Hours answer says a fermented plant juice from tobacco leaves "may act as a pesticide," and that it is harsh enough to need gloves. (Office Hours Ep. 17, 45:57)

Fermentation can strip a leaf's harsh compounds. Rhubarb leaves hold about 5% oxalic acid, and fermentation breaks it down. (Office Hours Ep. 122, 41:52)

If you ferment papaya anyway, gather the tips, unripe fruit, flowers, or ripe fruit. Mature leaves just make sugar. (Office Hours Oct 2025, 15:04)

Go easy on the sprayer. Too much fermented plant juice adds nitrogen, drives overgrowth, and makes plants more attractive to pests. (Office Hours Ep. 126, 39:37) For caterpillars on kale, the library's answer is calcium to harden the leaves. (Office Hours Ep. 74, 11:38)

The library does not say whether papaya leaf FPJ kills or repels any pest. It says nothing about papain.

1 more answer
josewalkertwd · Dec 16, 2021
Hi, searching about the extraction of papain, I found that you can scratch the skin of a green papaya with a knife (Not taking out the green papaya) to extract the papain, the process is repeated every 2 weeks and Mature fruits are discarted (may be used for some fpj or compost) , this will greatly decrease the production of papaya in this plant. For papain dilution mix it with water and use a filter, I haven’t tried it , maybe I’ll try it this week and let’s see what happens! that’s were I found it Peace ✌️ https://repositorio.uniandes.edu.co/bitstream/handle/1992/23586/u303039.pdf

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